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The European Journal of Public Health Advance Access originally published online on June 7, 2005
The European Journal of Public Health 2005 15(3):276-281; doi:10.1093/eurpub/cki080
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© The Author 2005. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

Health Services Research

Antibiotic prescription in primary health care: clinical and economic perspectives (Catalonia, Spain)

Josefina Caminal1 and Joan Rovira2

1 Universitat Autònoma de Barcelona, Catalonia, Spain
2 Human Development Network, World Bank, Washington, DC, USA

Correspondence: Josefina Caminal, MD, PhD, Universitat Autònoma de Barcelona, Facultat de Medicina. Medicina Preventiva i Salut Pública, Edifici M, 08193 Bellaterra (Cerdanyola) Barcelona, Spain, tel. +34 93 581 3802, fax +34 93 581 2344, Email: josefina.caminal{at}uab.es

Objective: To quantify clinical inappropriateness of antibiotic prescription and its costs in primary health care. Methods: 2470 cases of infectious disease during 1998 were analysed. Results: Of all cases, 69.9% did not require antibiotic treatment. Global clinical inappropriateness amounted to 43.7%, rising to 56.7% with the introduction of economic criteria. Treatment unnecessary but antibiotic provided (27.9%) represented the most important category. Costs of inappropriateness reached 68.4% of the estimated total cost. Conclusion: Appropriate antibiotic use should be focused on reducing antibiotic prescription when not indicated and restrainting the use of penicillins maintaining restrictive and adequate health policies, and also achieving co-responsibility from the general population.

Keywords: antibiotic prescription, clinical inappropriateness, costs of inappropriateness, primary health care


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