The European Journal of Public Health Advance Access originally published online on October 5, 2005
The European Journal of Public Health 2006 16(3):290-293; doi:10.1093/eurpub/cki201
Ethnic Disparities in Health |
Infant mortality, ethnicity, and genetically determined disorders in The Netherlands
Tom W.J. Schulpen1, Joke C.M. van Wieringen1, Pien J. van Brummen1, Jantien M. van Riel1, Frits A. Beemer2, Paul Westers3 and Jonne Huber4
1 Centre for migration and child health, University Medical Centre Utrecht, The Netherlands
2 Department of medical genetics, University Medical Centre Utrecht, The Netherlands
3 Centre for Biostatistics, Utrecht University, Utrecht, The Netherlands
4 Department of pathology, University Medical Centre Utrecht, The Netherlands
Correspondence: Prof. Tom W.J. Schulpen, MD, PhD, MPH, Paediatric Association of The Netherlands, PO Box 20059, 3502 LB Utrecht, The Netherlands, tel: +31 30 2823762, e-mail: Schulpen{at}worldonline.nl
Background: Infant mortality of ethnic minorities in The Netherlands (10% of the population) is twice as high as in the indigenous Dutch population. Causes of death are different for the diverse migrant groups. Methods: Hospital records of nearly 600 infants who died in the four major cities between 1995 and 1998 were analysed according to the cause of death, ethnicity, and possible hereditarity. Results: There was a four to five times higher proportion of hereditary causes of death in the Moroccan and Turkish population, compared with the Surinamese/Antillians and indigenous Dutch. Conclusions: This might be explained by a high inbreeding coefficient as three-quarters of the marriage partners are recruited from the home villages and between a quarter and a third of these marriages are between first cousins. Health promotion activities in The Netherlands have not been successful so far. Preconception genetic counselling might help in reducing these differences.
Keywords: consanguinity, ethnicity, genetics, infant mortality, The Netherlands