The European Journal of Public Health Advance Access originally published online on September 30, 2009
The European Journal of Public Health 2009 19(6):572-573; doi:10.1093/eurpub/ckp156
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© The Author 2009. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.
Commentaries |
Swine-origin influenza virus A(H1N1)v: lessons learnt from the early phase of the epidemic
Giovanni RezzaDepartment of Infectious Diseases, Istituto Superiore di Sanità, Roma, Italy
Correspondence: Giovanni Rezza, Department of Infectious Diseases, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Roma, Italy, tel: +39 06 4990 6125, fax: +39 06 4990 2755, e-mail: g.rezza@iss.it
Received August 14, 2009, accepted September 7, 2009
| The first 10% of the full text of this article appears below. |
In late March 2009, Mexican authorities identified an unexpected increase in the number of cases of influenza-like illness (ILI), including a higher than expected number of cases of severe pneumonia characterized by respiratory distress syndrome.1 At the beginning of April, a novel influenza virus A/(H1N1) variant (H1N1v) of apparent swine origin was identified by the US Centers for Disease Control and Prevention in two children in California.2 The same variant was then identified in Canada in biological samples from a Mexican patient with ILI. The evidence of sustained community transmission of H1N1v in different countries on more than one continent led the World Health Organization (WHO) to declare Phase 6 of pandemic alert (The Pandemic Phase).
H1N1v appears to