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The European Journal of Public Health Advance Access originally published online on May 12, 2006
The European Journal of Public Health 2006 16(6):601-608; doi:10.1093/eurpub/ckl062
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© The Author 2006. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

Infectious diseases

AIDS mortality before and after the introduction of highly active antiretroviral therapy: does it vary with socioeconomic group in a country with a National Health System?

Carme Borrell, Maica Rodríguez-Sanz, M. Isabel Pasarín, M. Teresa Brugal, Patricia García-de-Olalla, Marc Marí-Dell'Olmo and Joan Caylà

Agència de Salut Pública de Barcelona, Red de Centros de Epidemiología y Salud Pública (RCESP), Barcelona, Spain

Correspondence: Carme Borrell, Agència de Salut Pública de Barcelona, Pl. Lesseps 1, 08023 Barcelona, Spain, tel: +34-93-2384545, fax: +34-93-2173197, e-mail: cborrell{at}aspb.es

Background: The aim of this study is to determine whether socioeconomic AIDS mortality inequalities before and after the introduction of highly active antiretroviral therapy (HAART) have increased or decreased in a Spanish city where HAART is free. Methods: The study used a trend design, including all Barcelona residents older than 19 years of age. All AIDS deaths, which occurred among these residents between 1991 and 2001 were included. The variables studied were age, sex, socioeconomic (SES) group and HIV transmission group. AIDS age-standardized mortality rates for each year were estimated. Poisson regression models were fitted to obtain the relative risk (RR) of AIDS death for each socioeconomic group with respect to the reference group. Results: AIDS mortality increased up until 1995 and subsequently decreased due to the introduction of HAART. The increase in AIDS mortality was greater in the lowest SES group, which had higher rates and a RR of dying larger than that of the highest SES group, fact that remained fairly stable over the whole period. A similar pattern was observed in intravenous drug users. In the homosexual transmission group, rates for the lowest SES group were higher for the whole period and increased until 1996, while rates for the other SES groups were lower and decreased over the entire period. Conclusions: The fact that inequalities in AIDS mortality by SES group remained fairly stable for the whole period suggests that perhaps access to HAART, or adherence, is lower than desirable, in people of lower SES groups. These results ought to be taken into account when implementing treatment and prevention strategies.

Keywords: AIDS mortality, HAART therapy, socioeconomic inequalities, trends, urban area, Southern Europe


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